Ethno pharmacological study of medicinal plants used by local people in the Algerian Northern Sahara for the treatment of infertility

*Article not assigned to an issue yet


Research Articles | Published:

E-ISSN: 2229-4473.
Website: www.vegetosindia.org
Pub Email: contact@vegetosindia.org
DOI: 10.1007/s42535-025-01404-w
First Page: 0
Last Page: 0
Views: 147

Keywords: Ethno pharmacological study, Infertility, Medicinal plants, Algerian Northern Sahara


Abstract


An ethnobotanical survey was carried out among 164 interviews of the local population and herbalists of the Algerian northern Sahara region in order to inventory and identify the medicinal plants used in the treatment of infertility. The interviewees were of both sexes and aged between 35 and 45 years (37. 80%). According to the survey results. 56 species from 32 families are used in the treatment of infertility. with the most important families being Lamiaceae. Asteraceae. Apiaceous. Fabaceae. Brassicaceae and Zingiberaceae. Salvia Officinalis. Atriplex Halimus, Phoenix dactylifera L, Origanum majorana, Anastatica hierochuntica L, Lavandula officinalis, Cinnamomum verum, Lepidium sativum are the most cited species. The leaves are the most commonly used plant part (35. 4%). with infusion (70.3%) being the most popular preparation method. The majority of receipts (89.7%) are given orally. For plants used to treat ovaries cysts. The degree of agreement on medication (ICF) was very high (ICF = 0.80). This study is the first one in the Algerian north Sahara concerning female and male infertility. Several plants listed in this study have not yet been the subject of laboratory studies related to their beneficial effects on female and male fertility and could constitute interesting subjects of research. Phytochemical screening in the laboratory is necessary to know the chemical compounds contained in these plants and their degree of toxicity.

Ethno pharmacological study, Infertility, Medicinal plants, Algerian Northern Sahara


References


Andrade-Cetto A, Heinrich M (2011) From the field into labor: useful approach to selecting species based on local knowledge. Front Pharmacol 2:1–5. https://doi.org/10.3389/fphar.2011.00020.


Awan AA, Akhtar T, Ahmed MJ, Murtaza G (2021) Quantitative ethnobotany of medicinal plants uses in the Jhelum valley, Azad Kashmir, Pakistan. Acta Ecol Sin 41:88–96. https://doi.org/10.1016/j.chnaes.2020.09.002.


Azonbakin S, Dangbemey P, Osseni R et al (2021) Enquête ethnobotanique sur les plantes utilisées dans le traitement de l’infertilité masculine au Benin. Int J Biol Chem Sci 15:1667–1677. https://doi.org/10.4314/ijbcs.v15i4.28.


Basal WT, Issa AM, Abdelalem O, Omar AR (2023) Salvia officinalis restores semen quality and testicular functionality in cadmium-intoxicated male rats. Sci Rep 13:20808


Baziz K, Maougal RT, Amroune A (2020) An ethnobotanical survey of spontaneous plants used in traditional medicine in the region of Aures, Algeria. Eur J Ecol 6:49–69. https://doi.org/10.17161/eurojecol.v6i2.14669.


Behaz F, demnati F, Mebrek N, Belhadj A (2024) 2024 (DEDSPAZA), Algeria. 3 development of automatic and intelligent control systems in. J Pharm Pharmacogn Res 12:1143–1155. https://doi.org/10.56499/jppres24.2017_12.6.1143.


Belhaj S, Zidane L (2023) Ethnobotanical study of medicinal plants uses in the treatment of female infertility at the high atlas central of Morocco. Egypt J Bot 0:0–0. https://doi.org/10.21608/ejbo.2023.137055.1990.


Benarba B, Belabid L, Righi K et al (2015) Ethnobotanical study of medicinal plants used by traditional healers in Mascara (North West of Algeria). J Ethnopharmacol 175:626–637. https://doi.org/10.1016/j.jep.2015.09.030.


Benderraji L, Bounar R, Ghadbane M, Rebbas K (2021) Etude ethnobotanique comparative et utilisation thérapeutique de plantes médicinales de djebel djedoug (Hammam Dhalaa) et du milieu oasien (oasis de Boussaâda). J Oasis Agric Sustain Dev 3:1–12


Bendif H, Souilah N, Miara MD et al (2020) Medicinal plants popularly used in the rural communities of Ben Srour (Southeast of M’sila, Algeria). AgroLife Sci C J 9


Benkaddour M, Djahra AB, Benkherara S et al (2025) Ethnobotanical importance and Pharmacological properties of plants used in Southestern Algeria (El Oued) for the treatment of women’s infertility problems. J Herbs Spices Med Plants 1–17. https://doi.org/10.1080/10496475.2025.2500541.


Bibi S, Sultana J, Sultana H, Malik RN (2014) Ethnobotanical uses of medicinal plants in the highlands of Soan Valley, Salt Range, Pakistan. J Ethnopharmacol 155:352–361


Bouasla A, Bouasla I (2017) Ethnobotanical survey of medicinal plants in Northeastern of Algeria. Phytomedicine 36:68–81. https://doi.org/10.1016/j.phymed.2017.09.007.


Bouayyadi L, El Hafian M, Zidane L (2015) Étude floristique et ethnobotanique de la flore médicinale dans la région du Gharb, Maroc. J Appl Biosci 93:8760–8769. https://doi.org/10.4314/jab.v93i1.10.


Briguiche H, Zidane L (2019) Etude floristique et ethnobotanique des plantes médicinales utilisées dans le traitement des maladies de l’appareil respiratoire dans la région de Doukkala. Bull L’Institut Sci. 33–41


Byg A, Baslev H (2001) Diversity and use of palms in Zahamena, Eastern Madagascar. Biodivers Conserv 10:51–70. https://doi.org/10.1023/A:1016640713643.


Chehma A, Djebar MR, Hadjaiji F et al (2005) étude floristique spatio-temporelle des parcours sahariens du sud -est algérien. sécheresse 16:275–285


Cheriti A, Rouissat A, Sekkoum Balansard G (1995) Plantes de la pharmacopée traditionnelle dans la région d’El-Bayadh (Algérie). Fitoterapia 6:525–537


Chouabia A, Djemli S, Abdennour C et al (2021) Protective effect of Salvia officinalis against cypermethrininduced reprotoxicity in male wistar rats. Pharmacogn J 13:1413–1421. https://doi.org/10.5530/pj.2021.13.179.


Djahafi A, Taibi K, Ait Abderrahim L (2021) Aromatic and medicinal plants used in traditional medicine in the region of Tiaret, North West of Algeria. Mediterr Bot 42:e71465. https://doi.org/10.5209/mbot.71465.


Djerrou Z, Benyezzar-Kenana H, Maameri Z, Benhamza L (2022) An ethnopharmacological survey of medicinal plants used in the traditional treatment of human infertility in Eastern Algeria. Asian Pac J Reprod 11:77. https://doi.org/10.4103/2305-0500.341114.


Eddouks M, Hebi M, Ajebli M (2020) Medicinal plants and Gyneco-obstetric disorders among women in the South East of Morocco. Curr Women Health Rev 16:2–17. https://doi.org/10.2174/1573404815666191206112518.


Elfiky AM, Ibrahim RS, Khattab AR et al (2025) Exploring the therapeutic potential of marjoram (Origanum Majorana L.) in polycystic ovary syndrome: insights from serum metabolomics, network pharmacology and experimental validation. BMC Complement Med Ther 25:67. https://doi.org/10.1186/s12906-025-04774-5.


Farah R, Mahfoud HM, Mohamed DOH et al (2015) Ethnobotanical study of some medicinal plants from Hoggar, Algeria. J Med Plants Res 9:820–827. https://doi.org/10.5897/JMPR2015.5805.


Francis Xavier T, Kannan M, Auxilia A Francis Xavier, Kannan T, Auxilia M (2015) A. (2015). Observation on the traditional phytotherapy among the Malayali tribes in Eastern Ghats of Tamil Nadu, South India., 165, 198–214. J Ethnopharmacol 165:198–214


Ghorbani A (2005) Studies on pharmaceutical ethnobotany in the region of Turkmen Sahra, North of Iran (Part1):general results. J Ethnopharmacol 102:58–68. https://doi.org/10.1016/j.jep.2005.05.035.


Hadj-Seyd A, Kemassi A, Hadj Kouider Y, Harma A (2016) Traitement de l’infertilité: plantes spontanées du Sahara septentrional. Phytothérapie 14:241–245. https://doi.org/10.1007/s10298-015-1000-9.


Haghmorad D, Mahmoudi MB, Haghighi P et al (2019) Improvement of fertility parameters with tribulus terrestris and anacyclus pyrethrum treatment in male rats. Int Braz J Urol 45:1043–1054. https://doi.org/10.1590/s1677-5538.ibju.2018.0843.


Heinrich M, Edwards S, Moerman DE, Leonti M (2009) Ethnopharmacological field stud ies: a critical assessment of their conceptual basis and methods. J Ethnopharmacol 124:1–17


Jamila F, Mostafa E (2014) Ethnobotanical survey of medicinal plants used by people in Oriental Morocco to manage various ailments. J Ethnopharmacol 154:76–87. https://doi.org/10.1016/j.jep.2014.03.016.


Jdaidi N, Hasnaoui B (2016) Étude floristique et ethnobotanique des plantes médicinales au nord-ouest de la tunisie: cas de la communauté d’ouled Sedra. JARST 3:281–291


Kouider H, Mohammed B, Mohammed M, Abdelkarim R (2019) Importance des plantes medicinales pour la population rurale du parc national de djebel aissa (Sud Ouest Algerien)


Meddour R, Meddour-Sahar O (2016) Medicinal plants and their traditional uses in Kabylia (Tizi Ouzou, Algeria). Arab J Med Arom Plants 1:137–151. https://doi.org/10.48347/IMIST.PRSM/ajmap-v1i2.4331.


Meddour R, Sahar O, Ouyessad M (2020) Enquête ethnobotanique des plantes médicinales dans le parc national du djurdjura et sa zone d’influence, Algérie. Ethnobot Res Appl 20:1–25. https://doi.org/10.32859/era.20.46.1-25.


Merouane A, Fellag S, Touaibia M, Beldi A (2022) A ethnobotanical survey of medicinal plants consumed during holy month of Ramadan in Chlef region, Algeria. Ethnobot Res Appl 23:1–14. https://doi.org/10.32859/era.23.29.1-14.


Miara MD, Bendif H, Ait Hammou M, Teixidor-Toneu L (2018) Ethnobotanical survey of medicinal plants used by nomadic peoples in the Algerian steppe. J Ethnopharmacol 219:248–256


Nazim B, Adi̇L S, Yassi̇Ne M et al (2023) Herbal remedies used for the treatment of infertility in females by traditional healers in the Northwest of Algeria. Curr Perspect Med Aromat Plants CUPMAP. https://doi.org/10.38093/cupmap.1364913.


Nesrine H, Radia D, Lamia B, Bilal M (2022) The medicinal plants of the region of El Oued (South-Eastern Algeria): inventory and traditional uses. PLANT Arch 22:357–365. https://doi.org/10.51470/PLANTARCHIVES.2022.v22.no2.062.


Ogunlakina AD, Sonibare MA (2020) Ethnobotanical survey of medicinal plants used as remedy for female infertility and menstrual disorder in Southwestern Nigeria. Niger J Pharm Res 15:205. https://doi.org/10.4314/njpr.v15i2.8.


Oueld El hadj MD, Hadj Mohammed M, Zabeirou H, Chehma A (2003) Importance des plantes spontanées médicinale traditionnelle dans la pharmacopée de La région d’ouargla (Sahara septentrional–Est algérienne). Rev Sci Technol Univ Mentouri–Constantine- 20:73–78


Ozenda P (1958) Flore du Sahara septentrional et central. CNRS. Paris, France


Ozenda P (1983) Flore du Sahara., 2eme edit. Centre National de la Recherche Scientifique (C.N.R.S, Paris, France


Ozenda P (1991) Flore et végétation du Sahara, 3. ed. (mise à jour et augm.) de la Flore du Sahara. Ed. du Centre National de la Recherche Scientifique, Paris


Phillips O, Gentry AH, Reynel C et al (1994) Quantitative ethnobotany and Amazonian conservation. Conserv Biol 8:225–248. https://doi.org/10.1046/j.1523-1739.1994.08010225.x.


Quézel P, Santa S (1962) New flora of Algeria and Southern desert regions. CNRS. Paris, France


Rashid S, Zafar M, Khan MA et al (2014) An ethnobotanical study of medicinal plants in high mountainous region of Chail Valley (District Swat Pakistan). J Ethnobiol Ethnomed 10(1):36. https://doi.org/10.1186/1746-4269-10-36.


Rebbas K, Bounar R (2014) Études floristique et ethnobotanique des Plantes médicinales de La région de m’sila (Algérie). Phytothérapie 12:284–291


Redouan FZ, Benitez G, Picone RM et al (2020) Traditional medicinal knowledge of Apiaceae at Talassemtane National park (Northern Morocco). South Afr J Bot 131:118–130. https://doi.org/10.1016/j.sajb.2020.02.004.


Rehman K, Mashwani ZUR, Khan MA et al (2015) An ethnobotanical perspective of traditional medicinal plants from the Khattak tribe of Chonthra karak, Pakistan. J Ethnopharmacol 156:251–259. https://doi.org/10.1016/j.jep.2015.02.035.


Saadi B, Msanda F, Boubaker H (2013) Contributions of folk medicine knowledge in south-western Morocco: the case of rural communities of Immouzzer Ida Ou Tanane region. Int J Med Plant Res 2:135–145


Sabah Chermat, R Gharzouli (2015) Ethnobotanical study of medicinal flora in the North East of Algeria - an empirical knowledge in Djebel Zdimm (Setif). J Mater Sci Eng A; 5. https://doi.org/10.17265/2161-6213/2015.1-2.007.


Sargin SA, Selvi A, Büyükcengiz M (2015) Ethnomedicinal plants of Aydincik district of Mersin, Turkey. J Ethnopharmacol 174:200


Sarri M, Mouyet FZ, Benziane M, Cheriet A (2014) Traditional use of medicinal plants in a city at steppic character (M’sila, Algeria). J Pharm Pharm Res 2:31–35


Selmani C, Chabane D, Bouguedoura N (2017) Ethnobotanical survey of Phoenix dactylifera L. pollen used for the treatment of infertility problems in Algerian oases. Afr J Tradit Complement Altern Med 14:175–186


Slighoua M, Mahdi I, Amrati FE et al (2020) Ethnopharmacological survey of medicinal plants used in the traditional treatment of female infertility in Fez region. Morocco Phytothérapie 18:321–339. https://doi.org/10.3166/phyto-2019-0194.


Trotter RT, Logan MH (1986) A new approach for identifying potentially effective medicinal plants. Plants in indigenous medicine and diet, behavioural approaches. Bedford Hills, New York


Vitalini S, Iriti M, Puricelli C et al (2013) Traditional knowledge on medicinal and food plants used in Val San Giacomo (Sondrio, Italy)—an alpine ethnobotanical study. J Ethnopharmacol 145:517–529. https://doi.org/10.1016/j.jep.2012.11.024.


World Health Organization (2023) 1 in 6 people globally affected by infertility: WHO. https://www.who.int/news/item/04-04-2023-1-in-6-people-globally-affected-by-infertility. Accessed 21 Jun 2025


Wuttke W, Jarry H, Christoffel V et al (2003) Chaste tree (Vitex agnus-castus)–pharmacology and clinical indications. Phytomedicine 10:348–357


Zatout F, Benarba B, Bouazza A et al (2021) Ethnobotanical investigation on medicinal plants used by local populations in Tlemcen National Park(extreme North West Algeria). Mediterr Bot 15:12. https://doi.org/10.5209/mbot.69396.




 


Author Information


Department of Cellular and Molecular Biology, Faculty of Natural and Life Sciences, University of El Oued, El-Oued, Algeria