Starch nanocrystals from cassava peel and their use as carrier system for quercetin

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Research Articles | Published:

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DOI: 10.1007/s42535-024-01125-6
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Keywords: Starch nanocrystals, Cassava peel, Thermal stability, Quercetin, Drug delivery


Abstract


Starch is a renewable, biodegradable and natural polymer obtained from many plants, which is a source of stored energy. It is the second most plentiful biomass material in nature. This can be isolated in the form of micro-scale granules from plants. In recent years, starch nanocrystals are considered as one of the promising biomaterials for innovative utilization in foods, pharmaceuticals, cosmetics and various nanocomposites. Thus, in this study, starch was extracted and converted into nanocrystals by the acid hydrolysis method from Manihot esculenta. FTIR spectrum confirmed no changes in the structure of starch nanocrystals even after acid hydrolysis compared to native starch. HR-TEM with SAED pattern revealed the obtained particle sizes between 50 and 100 nm that are crystalline in nature. XRD analysis confirmed the crystalline nature of starch nanocrystals. The decreased thermal stability was observed for starch nanocrystals after recrystallization compared to native starch. The encapsulation efficiency of Quercetin on starch nanocrystals was found to be 81% after the third wash. Furthermore, controlled release of quercetin was observed (84%) in 24 h.

Starch nanocrystals, Cassava peel, Thermal stability, Quercetin, Drug delivery


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Author Information


Department of Biotechnology, Kumaraguru College of Technology, Coimbatore, India