Vegetos
(An International Journal of Plant Research & Biotechnology)
Phytochemical profile and GC–MS analysis from different parts of Terminalia chebula Retz. and Terminalia bellirica (Gaertn.) Roxb
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Research Articles | Published: 06 November, 2024
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Keywords: Composition, Phytochemicals, Pharmaceutical, Trees
Abstract
Plants are excellent sources of functionally bioactive compounds and essential nutrients. Terminalia chebula Retz. and Terminalia bellirica (Gaertn.) Roxb. are very promising plants belonging to the family Combretaceae and are extensively used as ethnomedicinal and traditional plants. Qualitative and quantitative screening of aqueous and 50% ethanolic extracts showed various phytochemical groups. Results revealed that extracts of different plant parts had a different colour, consistency and phytochemical group composition, where the ethanolic fruit extracts of T. chebula and T. bellirica species had the highest phenolic content of 15.80 mg GAE/g and 15.16 mg GAE/g respectively. The total antioxidant activity was highest in the fruit extract of T. chebula 5.09 mg AAE/g and lowest in the bark aqueous extract of T. bellirica (2.38 mg AAE/g). GC–MS analysis of dried powder of selected species revealed the presence of various volatile and semi-volatile compounds with potential therapeutic applications. Characteristic peaks associated with phenols, carboxylic acids, alkenes, glycogen, alkyl halides, halogens, aliphatic amines, primary and secondary amines, esters, ethers, aromatics and silicon compounds were detected.
References
Abraham A, Mathew L, Samuel S (2014) Pharmacognostic studies of the fruits of Terminalia bellirica (Gaertn.) Roxb. J Pharm Phytochem 3(2):45–52
Balabaa SI, Zaki AY, El Shamy AM (1974) Total flavonoid and rutin content of the different organs of Sophora japonica L. J Assoc Anal Chem 57(3):752–755
Bhattacharyya PN, Jha DK (2011) Antidermatophytic and antioxidant activity of Terminalia arjuna (Roxb.) Wight & Arn. bark. Int J Res Pharm Biol Arch 2:973–979
Bray HG, Thorpe W (1954) Analysis of phenolic compounds of interest in metabolism. Meth Biochem Anal 1:27–52
Bruce F (2013) Edible Terminalia fruit and nuts. Food Plants Int 3–39.
Cock IE (2015) The medicinal properties and phytochemistry of plants of the genus Terminalia (Combretaceae). Inflammopharmacology 23(5):203–229
Das G, Kim DY, Fan C, Gutiérrez-Grijalva EP, Heredia JB, Nissapatorn V, Mitsuwan W, Pereira ML, Nawaz M, Siyadatpanah A, Norouzi R, Sawicka B, Shin HS, Patra JK (2020) Plants of the genus terminalia: an insight on its biological potentials. Pre-Clin Clin Stud Front Pharmacol 8(11):561248. https://doi.org/10.3389/fphar.2020.561248
Debnath S, Dey D, Hazra S, Ghosh S, Ray R, Hazra B (2013) Antibacterial and antifungal activity of Terminalia arjuna Wight & Arn. bark against multi-drug resistant clinical isolates. J Coast Life Med 1(4):315–321
Guleria S, Tiku AK, Rana S (2010) Antioxidant activity of acetone extract/fractions of Terminalia bellerica Roxb. fruit. Indian J Biochem Biophys 47:110–116
Gupta D, Kumar M (2017) Evaluation of in vitro antimicrobial potential and GC–MS analysis of Camellia sinensis and Terminalia arjuna. Biotechnol Rep 13:19–25
Gupta A, Kumar R, Kumar S, Pandey AK (2017) Pharmacological aspects of Terminalia bellirica. In: Mahdi AA, Abid M, Khan MMA, Ansari MI, Maheshwari RK (eds) Molecular biology and pharmacognosy of beneficial plants. Lenin Media Private Limited, Delhi, India, pp 52–64
Kaur S, Jaggi RK (2010) Antinociceptive activity of chronic administration of different extracts of Terminalia bellerica Roxb. and Terminalia chebula Retz. fruits. Indian J Exp Biol 48(9):925–930
Kumar S, Ahmad MK, Waseem M, Pandey AK (2015) Drug targets for cancer treatment: an overview. Med Chem 5(3):115–123
Kumar R, Singh AK, Gupta A, Bishayee A, Pandey AK (2019) Therapeutic potential of Aloe vera—a miracle gift of nature. Phytomedicine 60:152996
Pisoschi AM, Negulescu GP (2011) Methods for total antioxidant activity determination: a review. Anal Biochem 1(1):106
Rao A, Zhang Y, Muend S, Rao R (2010) Mechanism of antifungal activity of terpenoid phenols resembles calcium stress and inhibition of the TOR pathway. Antimicrob Agents Chemother 54(12):5062–5069
Saleem A, Husheem M, Härkönen P, Pihlaja K (2002) Inhibition of cancer cell growth by crude extract and the phenolics of Terminalia chebula retz. fruit. J Ethnopharm 81(3):327–336
Shamsa F, Monsef H, Ghamooshi R, Verdian-Rizi M (2008) Spectrophotometric determination of total alkaloids in some Iranian medicinal plants. Thai J Pharm Sci 32:17–20
Singh A, Bajpai V, Kumar S, Kumar B, Srivastava M, Rameshkumar KB (2016) Comparative profiling of phenolic compounds from different plant parts of six Terminalia species by liquid chromatography–tandem mass spectrometry with chemometric analysis. Ind Crops Prod 87:236–246
Subhasree B, Baskar R, Keerthana RL, Susan RL, Rajasekaran P (2009) Evaluation of antioxidant potential in selected green leafy vegetables. Food Chem 115(4):1213–1220
Sultan MT, Anwar MJ, Imran M, Khalil I, Saeed F, Neelum S, Al-Jbawi E (2023) Phytochemical profile and pro-healthy properties of Terminalia chebula: a comprehensive review. Intl J Food Properties 26(1):526–551
Sultana B, Anwar F, Ashraf M (2009) Effect of extraction solvent/technique on the antioxidant activity of selected medicinal plant extracts. Molecules 14(6):2167–2180
Thakur S, Singla A, Chhabra R, Kaur M, Gupta N, Bhardwaj U, Sharma JP (2023) GC-MS analysis for phytochemical profiling of different Salix clones. Russ J Pl Physiol 70(6):122. https://doi.org/10.1134/S1021443723600708
Venkatesan A, Kathirvel A, Prakash S, Sujatha V (2017) Antioxidant, antibacterial activities and identification of bioactive compounds from Terminalia chebula bark extracts. Free Radic Antioxid 7(1):43–49
Author Information
Department of Botany, Punjab Agricultural University, Ludhiana, India