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Keywords: n M. indican , Therapeutic, Medicinal plant, Nutritional composition, Anaphylactic
The anaphylactic and therapeutic properties of medicinal plants have been associated with the presence of bioactive phytochemicals that have specific pharmacological and physiological effects on humans. The aim of this research was to estimate the phytochemicals and nutritional components in the stem bark of Mangifera indica which may be responsible for its bioactive and pharmacological properties and to support the acclaimed traditional use of this plant in the treatment of some ailments. Proximate analysis (nutritional composition) and phytochemical analysis of the stem bark were done using previously reported standard methods. Phytochemical analysis in mg/100 g gave saponin 3.19 ± 0.13, tannin 4.95 ± 0.27, flavonoid3.15 ± 0.12, alkaloid 7.09 ± 0.16, oxalate 18.09 ± 0–13, anthraquinone 1.38 ± 0.20, phytate 1.86 ± 0.5 and cyanogenic glycosides 0.77 ± 0.02. The proximate analysis gave moisture content of 6.07% ± 0.12, ash content 2.645% ± 0.29, crude fibre 3.95% ± 0.04, crude lipid 1.54% ± 0.03, crude protein 9.44% ± and carbohydrate 75.97% ± 0.19. The acclaimed use of M. indica stem bark in traditional medicine to treat and manage various infections and diseases may add to its phytochemical and nutritional composition.
Abdallah EM, Alhatlani BY, de Paula Menezes R, Martins CHG (2023) Back to nature: medicinal plants as promising sources for antibacterial drugs in the post-antibiotic era. Plants 12(17):3077. https://doi.org/10.3390/plants12173077
Abera S, Yohannes W, Chandravanshi BS (2023) Effect of processing methods on antinutritional factors (oxalate, phytate, and tannin) and their interaction with minerals (calcium, iron, and zinc) in red, white, and black kidney beans. Int J Anal Chem 2023:1–11. https://doi.org/10.1155/2023/6762027
Ahmad R, Alqathama A, Aldholmi M, Riaz M, Abdalla AN, Aljishi F, Althomali E, Amir M, Abdullah O, Alamer MA, Alaswad D, Alsulais W, Alsulays A (2023) Antidiabetic and anticancer potentials of Mangifera indica L. from different geographical origins. Pharmaceuticals 16(3):350. https://doi.org/10.3390/ph16030350
Al-Khayri JM, Rashmi R, Toppo V, Chole PB, Banadka A, Sudheer WN, Nagella P, Shehata WF, Al-Mssallem MQ, Alessa FM, Almaghasla MI, Rezk AA-S (2023) Plant secondary metabolites: the weapons for biotic stress management. Metabolites 13(6):716. https://doi.org/10.3390/metabo13060716
Ambu G, Chaudhary RP, Mariotti M, Cornara L (2020) Traditional uses of medicinal plants by ethnic people in the Kavrepalanchok District. Central Nepal Plants 9(6):759. https://doi.org/10.3390/plants9060759
Asase A (2023) Ghana’s herbal medicine industry: prospects, challenges and ways forward from a developing country perspective. Front Pharmacol. https://doi.org/10.3389/fphar.2023.1267398
Buathong R, Duangsrisai S (2023) Plant ingredients in Thai food: a well-rounded diet for natural bioactive associated with medicinal properties. PeerJ 11:e14568. https://doi.org/10.7717/peerj.14568
Chen T, Qian B, Zou J, Luo P, Zou J, Li W, Chen Q, Zheng L (2023) Oxalate as a potent promoter of kidney stone formation. Front Med. https://doi.org/10.3389/fmed.2023.1159616
Edo GI, Ugbune U, Akpoghelie PO, Owheruo JO (2023) Evaluation of physicochemical, phytochemical, anti-bacterial and antioxidant potential of kola nut (cola acuminata): an approach in food, health and nutritional benefits. Vegetos. https://doi.org/10.1007/s42535-023-00715-0
Ganogpichayagrai A, Suksaard C (2020) Proximate composition, vitamin and mineral composition, antioxidant capacity, and anticancer activity of Acanthopanax trifoliatus. J Adv Phar Technol Res 11(4):179. https://doi.org/10.4103/japtr.JAPTR_61_20
Ganogpichayagrai A, Palanuvej C, Ruangrungsi N (2017) Antidiabetic and anticancer activities of Mangifera indica cv. Okrong leaves. J Adv Pharm Technol Res 8(1):19. https://doi.org/10.4103/2231-4040.197371
Heinrich M, Mah J, Amirkia V (2021) Alkaloids used as medicines: structural phytochemistry meets biodiversity—an update and forward look. Molecules 26(7):1836. https://doi.org/10.3390/molecules26071836
Kumar M, Saurabh V, Tomar M, Hasan M, Changan S, Sasi M, Maheshwari C, Prajapati U, Singh S, Prajapat RK, Dhumal S, Punia S, Amarowicz R, Mekhemar M (2021) Mango (Mangifera indica L.) leaves: nutritional composition, phytochemical profile, and health-promoting bioactivities. Antioxidants 10(2):299. https://doi.org/10.3390/antiox10020299
Kumar A, Kumar PN, Jose M, Tomer A, Oz V, Proestos E, Zeng C, Elobeid M, Oz F (2023) Major phytochemicals: recent advances in health benefits and extraction method. Molecules 28(2):887. https://doi.org/10.3390/molecules28020887
Lim KJA, Cabajar AA, Lobarbio CFY, Taboada EB, Lacks DJ (2019) Extraction of bioactive compounds from mango (Mangifera indica L. var. Carabao) seed kernel with ethanol–water binary solvent systems. J Food Sci Technol 56(5):2536–2544. https://doi.org/10.1007/s13197-019-03732-7
Marolt G, Kolar M (2020) Analytical methods for determination of phytic acid and other inositol phosphates: a review. Molecules 26(1):174. https://doi.org/10.3390/molecules26010174
Mitchell T, Kumar P, Reddy T, Wood KD, Knight J, Assimos DG, Holmes RP (2019) Dietary oxalate and kidney stone formation. Am J Physiol Renal Physiol 316(3):F409–F413. https://doi.org/10.1152/ajprenal.00373.2018
Najmi A, Javed SA, Al Bratty M, Alhazmi HA (2022) Modern approaches in the discovery and development of plant-based natural products and their analogues as potential therapeutic agents. Molecules 27(2):349. https://doi.org/10.3390/molecules27020349
Naqbi KM, Karthishwaran K, Kurup SS, Abdul Muhsen Alyafei M, Jaleel A (2022) Phytochemicals, proximate composition, mineral analysis and in vitro antioxidant activity of Calligonum crinitum Boiss Horticulturae 8(2):156. https://doi.org/10.3390/horticulturae8020156
Nwosu LC, Edo GI, Özgör E (2022) The phytochemical, proximate, pharmacological, GC-MS analysis of Cyperus esculentus (Tiger nut): a fully validated approach in health, food and nutrition. Food Biosci 46:101551. https://doi.org/10.1016/j.fbio.2022.101551
Pujol A, Sanchis P, Grases F, Masmiquel L (2023) Phytate intake, health and disease: “Let Thy Food Be Thy Medicine and Medicine Be Thy Food.” Antioxidants 12(1):146. https://doi.org/10.3390/antiox12010146
Riaz M, Khalid R, Afzal M, Anjum F, Fatima H, Zia S, Rasool G, Egbuna C, Mtewa AG, Uche CZ, Aslam MA (2023) Phytobioactive compounds as therapeutic agents for human diseases: a review. Food Sci Nutr 11(6):2500–2529. https://doi.org/10.1002/fsn3.3308
Rodeiro I, Delgado R, Garrido G (2014) Effects of a Mangifera indica L. stem bark extract and mangiferin on radiation-induced DNA damage in human lymphocytes and lymphoblastoid cells. Cell Prolifer 47(1):48–55. https://doi.org/10.1111/cpr.12078
Rodríguez Madrera R, Suárez Valles B (2021) Analysis of cyanogenic compounds derived from mandelonitrile by ultrasound-assisted extraction and high-performance liquid chromatography in Rosaceae and Sambucus families. Molecules 26(24):7563. https://doi.org/10.3390/molecules26247563
Roy A, Khan A, Ahmad I, Alghamdi S, Rajab BS, Babalghith AO, Alshahrani MY, Islam S, Islam MR (2022) Flavonoids a bioactive compound from medicinal plants and its therapeutic applications. Biomed Res Int 2022:1–9. https://doi.org/10.1155/2022/5445291
Stilinović N, Čapo I, Vukmirović S, Rašković A, Tomas A, Popović M, Sabo A (2020) Chemical composition, nutritional profile and in vivo antioxidant properties of the cultivated mushroom Coprinus comatus. Royal Soc Open Sci 7(9):200900. https://doi.org/10.1098/rsos.200900
Tong Z, He W, Fan X, Guo A (2022) Biological function of plant tannin and its application in animal health. Front Veterin Sci. https://doi.org/10.3389/fvets.2021.803657
Urugo MM, Tringo TT (2023) Naturally occurring plant food toxicants and the role of food processing methods in their detoxification. Int J Food Sci 2023:1–16. https://doi.org/10.1155/2023/9947841
Xue L, Otieno M, Colson K, Neto C (2023) Influence of the growing region on the phytochemical composition and antioxidant properties of North American Cranberry Fruit (Vaccinium macrocarpon Aiton). Plants 12(20):3595. https://doi.org/10.3390/plants12203595
Department of Biochemistry, Faculty of Science, Delta State University of Science and Technology, Ozoro, Nigeria