*Article not assigned to an issue yet
Ayyanar Muniappan, Krupa Jayaraj, Jenipher Christopher, Amalraj Singamoorthy, Gurav Shailendra S.
Keywords:
Antibacterial agents, Antioxidants, Flavonoids, n Moringaceaen , Phenolics
Moringa concanensis (Moringaceae) is an important folk medicinal plant widely used to treat various ailments. The present study was aimed to investigate the phytochemical screening, antioxidant and antibacterial properties of M. concanensis leaves using various solvents. Total phenolics content and flavonoid content were analysed by the spectrophotometric methods. Antioxidant activity was performed using nine in vitro assays and antibacterial activity was studied against nine pathogenic bacteria by agar disc diffusion method. The preliminary phytochemical analysis showed the presence of steroids, triterpenoids, reducing sugar, sugar, alkaloids, phenolic, flavonoid, saponins, and tannins. The methanolic and ethyl acetate extracts of M. concanensis leaves showed highest amount of total phenolic content of 152.81 ± 3.30 and 136.52 ± 3.36 mg GAE/g, total flavonoid content of 123.22 ± 6.5 and 130.83 ± 8.69 mg QE/g respectively. Methanolic and ethyl acetate extracts showed the strongest DPPH, ABTS, hydroxyl, hydrogen peroxide free radical scavenging, and ferric-reducing power. For antibacterial activity also, ethyl acetate and methanolic extracts exhibited superior inhibition levels against the tested bacterial strains, like Escherichia coli (24.0 ± 0.1 mm) and Pseudomonas aeruginosa (25.1 ± 0.3 mm). The findings provide baseline information that tends to support the potential use of M. concanensis as a therapeutic agent in treating various diseases and could be a potential natural antioxidant in slowing oxidative stress and related disorders.
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We thank the Management and Principal of A.V.V.M. Sri Pushpam College, Poondi, Thanjavur, India for providing facilities and encouragement.