Detection of chemical compounds by GC–MS and evaluation of antioxidant, anti-inflammatory, antibacterial and anti-cancer potential in methanolic extracts of Corallocarpus epigaeus (Rottler) Hook. f.

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DOI: 10.1007/s42535-025-01564-9
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Keywords: n Corallocarpus epigaeusn , Gas chromatography-mass spectroscopy, Methanolic extracts, Phytoconstituents, Bioactive compounds


Abstract

The Gas Chromatography-Mass Spectroscopy (GC–MS) technique was used in the present work to identify bioactive compounds found in various plant parts of Corallocarpus epigaeus (C. epigaeus). Corallocarpus epigaeus is rich in many phytochemicals such as phenols, steroids, flavonoids, alkaloids, and tannins. The samples were rinsed, dried, and pulverized into a powder. The powdered leaf, stem, and root were combined with methanol and incubated for 48 h using cold maceration technique. Chromatograms and bioactive parameters of methanolic extracts from the leaves, stem and roots of C. epigaeus were obtained using the GC–MS method. According to chromatogram analysis, 8 compounds in leaf methanolic extracts; stem methanolic extracts 14 and root methanolic extracts 20 bioactive compounds were identified. Among the above, these are key bioactive compounds Lupeol, Phytol, Glycocholic acid, n- Hexadecanoic acid, 9-octadecenoic acid methyl ester, Stigmasterol, B-sitosterol, Diethyl Phthalate, Dimethyl sulfoxided, Allomatrine, Hexadecanoic acid methyl ester, 9,12-Octadecadienoic acid (Z, Z), methyl ester, Melezitose, 3-O-Methyl-d-glucose, n-Hexadecanoic acid derivatives are synthesized from leaf, stem and root explants of C. epigaeus. These designated chemicals have biological properties that may combat the incurable human illnesses.

n Corallocarpus epigaeusn , Gas chromatography-mass spectroscopy, Methanolic extracts, Phytoconstituents, Bioactive compounds


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Author Information

Department of Biotechnology, Kakatiya University, Warangal, India